The β-galactosidase enzyme from Bacillus circulans ATCC 31382 is a member of Glycoside Hydrolase family 2. This microbial enzyme also known as BgaD is widely used as a biocatalyst in the food industry for the production of prebiotic galactooligosaccharides (GOS) from lactose. GOS mixtures mimic the prebiotic effects of the human milk oligosaccharides, and therefore are added to infant formula. The GOS product synthesized by BgaD-D presents a carbohydrate mixture showing β(1→4), β(1→2), β(1→3), β(1→6) linked galactose on the reducing glucose residue, containing both linear and branched structures. These structures can be further elongated with β(1→4)-linked galactose residues.

Human newborns are capable to produce β-galactosidase enzymes to digest lactose. Nevertheless, the majority of adults have lost the ability to produce these enzymes. This can end up in lactose intolerance, making them incapable to digest dairy products. The lactose could be removed from the milk to solve this problem, and the residual product could be converted to high valuable lactose derivates like GOS.

This product is sold for research use only.
*Activity was measured by following the release of glucose from lactose. One unit of enzyme activity is defined as the release of 1 μmol of substrate per minute.